A Rare Case of Eisenmenger Syndrome Complicated by Dengue Hemorrhagic Fever

Felly Moelyadi; Hendrata Erry Andisari

doi:10.56951/q2rncj89

A Rare Case of Eisenmenger Syndrome Complicated by Dengue Hemorrhagic Fever

Penulis

Felly Moelyadi Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia
Hendrata Erry Andisari Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia dan Department of Internal Medicine, dr. Ramelan Naval Central Hospital, Surabaya, East Java, Indonesia

DOI:

https://doi.org/10.56951/q2rncj89

Kata Kunci:

Sindrom Eisenmenger, Hipertensi pulmonal, Demam berdarah dengue, kelainan jantung

Abstrak

Latar Belakang: Sindrom Eisenmenger (SE) merupakan komplikasi langka dari penyakit jantung bawaan yang ditandai dengan hipertensi pulmonal serta pirau dua arah atau terbalik. Pasien dengan SE rentan terhadap infeksi, termasuk virus dengue (DENV), yang dapat memperburuk kondisi kardiovaskular. Kasus: Seorang wanita berusia 32 tahun dengan riwayat penyakit jantung bawaan datang dengan keluhan sesak napas, sianosis, palpitasi, dan muntah. Selama perawatan, pasien mengalami demam, ruam, petekie, serta trombositopenia. Ekokardiografi menunjukkan adanya defek septum atrium dengan pirau dua arah dan hipertensi pulmonal, sesuai dengan diagnosis SE. Pemeriksaan laboratorium menegakkan diagnosis demam berdarah dengue (DBD) dengan hemokonsentrasi dan trombositopenia berat. Terapi yang diberikan meliputi resusitasi cairan hati-hati, transfusi trombosit, kortikosteroid, serta terapi suportif sildenafil sitrat untuk hipertensi pulmonal. Kondisi pasien membaik dan dipulangkan setelah sembilan hari perawatan. Kesimpulan: Kasus ini menggambarkan interaksi kompleks antara SE dan DBD, di mana peningkatan permeabilitas vaskular, kelainan koagulasi, dan hipoksemia kronis memperberat ketidakstabilan hemodinamik. Hingga saat ini, belum terdapat pedoman baku untuk penatalaksanaan DBD pada pasien SE sehingga terapi perlu disesuaikan secara individual dengan pemantauan ketat. Pengenalan komorbiditas langka ini penting untuk mencegah komplikasi, mengoptimalkan terapi, serta meningkatkan kelangsungan hidup.

Unduhan

Baca Selengkapnya

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