Coronary Atherosclerotic Calcification
DOI:
https://doi.org/10.56951/00pm8d52Kata Kunci:
penyakit arteri koroner, kalsifikasi aterosklerosis, kalsifikasi arteri koronerAbstrak
Penyakit arteri koroner merupakan masalah kesehatan masyarakat yang signifikan di Asia Tenggara, termasuk Indonesia. Penyakit ini ditandai oleh penumpukan plak aterosklerotik di dalam arteri koroner, yang menyebabkan aliran darah ke miokardium berkurang atau terhenti. Salah satu ciri khas aterosklerosis adalah adanya kalsifikasi, yang dapat terjadi selama progresi maupun regresi plak. Hingga saat ini, pola perkembangan lesi aterosklerotik belum sepenuhnya jelas apakah mengikuti urutan dengan pola linear. Pembentukan mikrokalsifikasi memulai proses kalsifikasi dan memerlukan
penelitian lebih lanjut. Beberapa modalitas pencitraan yang telah berkembang pesat dapat membantu mengukur beban kalsifikasi arteri koroner dan memandu manajemen yang tepat. Isu tentang paparan radiasi telah menjadikan pencitraan kalsium arteri koroner sebagai parameter yang paling efektif, efisien, dan mudah diamati di antara teknik pencitraan invasif dan non-invasif. Mengidentifikasi karakteristik plak berisiko tinggi serta kalsifikasi yang berat atau ekstensif sangat penting untuk memberikan tata laksana yang optimal. Namun, perkembangan kalsifikasi masih belum pasti, dan penelitian terus
dilakukan untuk mengeksplorasi metode potensial yang dapat membalikkan proses ini. Berbagai alat dan teknik kompleks telah dikembangkan untuk menangani berbagai jenis lesi yang mengalami kalsifikasi. Penelitian lebih lanjut diperlukan untuk mengidentifikasi pasien yang mengalami perkembangan kalsifikasi yang lebih cepat, untuk mengoptimalkan strategi pencegahan.
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Hak Cipta (c) 2024 Sony Hilal Wicaksono, Christian Setiawan, Indah Fitriani
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