Potensi farmakologi Kasumba Turatea (Carthamus tinctorius L.) sebagai antibakteri

Penulis

  • Lismayana Hansur Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Makassar dan Ilmu Biomedik, Fakultas Kedokteran, Universitas Indonesia, Jakarta
  • Ami Febriza Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Makassar
  • Dito Anurogo Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Makassar dan International PhD Program for Cell Therapy and Regeneration Medicine (IPCTRM), College of Medicine, Taipei Medical University (TMU), Taiwan
  • Dara Ugi Aras Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Makassar
  • Endah Dwijayanti Jurusan Kimia, Fakultas MIPA, Universitas Islam Makassar

DOI:

https://doi.org/10.56951/6zstjd88

Kata Kunci:

Carthamus tinctorius L., antibakteri, hydroxysafflor yellow A, antioksidan, ekstrak

Abstrak

Kasumba turatea (Carthamus tinctorius L.) merupakan tanaman yang banyak digunakan dalam pengobatan tradisional di Sulawesi Selatan. Kandungan utama dalam bunga C. tinctorius L. adalah hydroxysafflor yellow A yang berfungsi sebagai agen antiinflamasi, antioksidan, dan penghambat agregasi platelet. Tinjauan pustaka ini bertujuan untuk
menganalisis potensi farmakologi C. tinctorius L. sebagai agen antibakteri. Metode yang digunakan melibatkan tinjauan pustaka dari berbagai database seperti PubMed, Google Scholar, dan Scopus. Hasil tinjauan pustaka ini menunjukkan bahwa ekstrak C. tinctorius L. memiliki kemampuan untuk menghambat pertumbuhan berbagai bakteri patogen seperti Listeria monocytogenes, Streptococcus iniae, Staphylococcus aureus, dan Escherichia coli. Senyawa bioaktif seperti carthamin, senyawa fenolik, dan flavonoid menunjukkan aktivitas antibakteri secara in vitro. Selain itu, ekstrak C. tinctorius L. juga memiliki potensi sebagai agen antihelmintik dan antioksidan. Penelitian lebih lanjut diperlukan untuk mengisolasi
dan mengkarakterisasi senyawa bioaktif spesifik serta validasi in vivo dan uji klinik untuk memastikan efektivitas dan keamanannya. 

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Diterbitkan

01-07-2024

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[1]
Potensi farmakologi Kasumba Turatea (Carthamus tinctorius L.) sebagai antibakteri. MEDICINUS 2024;37:41-6. https://doi.org/10.56951/6zstjd88.