Kromoblastomikosis Penyakit Jamur Yang Terabaikan

Danu Yuliarto; Achmad Satya Negara; Harijono Kariosentono; Nugrohoaji Dharmawan; Nurrachmat Mulianto

doi:10.56951/medicinus.v36i1.116

Kromoblastomikosis Penyakit Jamur Yang Terabaikan

Penulis

Danu Yuliarto Departemen Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta
Achmad Satya Negara Departemen Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta
Harijono Kariosentono Departemen Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta
Nugrohoaji Dharmawan Departemen Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta
Nurrachmat Mulianto Departemen Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta

DOI:

https://doi.org/10.56951/medicinus.v36i1.116

Kata Kunci:

Kromoblastomikosis, penyakit terabaikan, sel muriform

Abstrak

Kromoblastomikosis merupakan infeksi jamur profunda pada kulit dan jaringan subkutan yang disebabkan oleh jamur berpigmen atau jamur dematiaceous. Penyakit ini merupakan endemi di daerah tropis dan subtropis seperti Asia, Afrika, dan Amerika Latin. Kromoblastomikosis lebih banyak ditemukan pada laki-laki dewasa yang bekerja di area pertanian, tukang kebun, maupun tukang kayu. Diagnosis kromoblastomikosis ditegakkan melalui pemeriksaan kerokan kulit, kultur mikroskopik, atau ditemukan sel muriform atau medlar bodies pada pemeriksaan histopatologi maupun kultur. Gambaran klinis bervariasi, lesi awal berupa papul yang menyebar secara lambat selama beberapa bulan sampai tahun, kemudian lesi akan membentuk suatu plak dengan bagian tengah atropi. Banyak pasien tidak terdiagnosis pada tahap awal perkembangan penyakit dikarenakan tahap ini jarang terlihat. Pengobatan kromoblastomikosis meliputi pembedahan lesi awal dan terapi farmakologis dengan agen antifungal seperti itraconazole, yang paling umum digunakan dalam pengobatan kromoblastomikosis. Prognosis kromoblastomikosis tidak terlalu baik, kecuali pada lesi yang baru.

Unduhan

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