Modalitas Terapi Vitiligo Pada Anak
DOI:
https://doi.org/10.56951/medicinus.v35i3.106Kata Kunci:
vitiligo, anak, autoimun, repigmentasiAbstrak
Vitiligo merupakan gangguan pigmentasi berupa bercak putih tidak berpigmen pada kulit dan rambut akibat hilangnya fungsi melanosit. Vitiligo pada anak umumnya berhubungan dengan penyakit autoimun lain dan memberikan efek gangguan kosmetik serta psikososial yang serius. Modalitas terapi vitiligo pada anak terdiri dari terapi topikal, fototerapi, terapi sistemik, dan pembedahan. Vitiligo pada anak memiliki prognosis yang relatif baik dibandingkan dengan pada orang dewasa. Repigmentasi pada kasus vitiligo anak umumnya terjadi secara spontan dan kasus relapse jarang sekali didapatkan.
Unduhan
Referensi
Spritz R, Andersen G. Genetics of vitiligo. Dermatol Clin. 2017;35(2):245–55. DOI: https://doi.org/10.1016/j.det.2016.11.013
Speeckaert R, Van Geel N. Vitiligo: An update on pathophysiology and treatment options. Am J Clin Dermatol. 2017;18(6):733–44. DOI: https://doi.org/10.1007/s40257-017-0298-5
Nicolaidou E, Mastraftsi S, Tzanetakou V, Rigopoulos D. Childhood vitiligo. Am J Clin Dermatol. 2019;20(4):515–26. DOI: https://doi.org/10.1007/s40257-019-00430-0
Chauhan PS, Sharma H, Dhattarwal N, Mahajan VK, Mehta KS, Sharma A, dkk. Characteristics of vitiligo in children and adolescents. Skinmed. 2020;18(5):278–85.
Dwiyana RF, Marindani V, Agustina R, Setiawan, Idjradinata PS, Sutedja E. Clinico-epidemiological profile of vitiligo patients in Dr. Hasan Sadikin General Hospital Bandung. Maj Kedokt Bandung. 2017;49(2):132–8. DOI: https://doi.org/10.15395/mkb.v49n2.1056
Lotti T, D'Erme AM. Vitiligo as a systemic disease. Clinics in dermatology. 2014;32(3):430-4.
Dhar S, Srinivas SM. Pediatric vitiligo. Dalam : Relhan V, Garg VK, Ghunawat S, Mahajan K, penyunting. Comprehensive Textbook on Vitiligo. Edisi ke-1. Boca Raton: CRC Press; 2021.h.71–5.
Ezzedine K, Silverberg N. A practical approach to the diagnosis and treatment of vitiligo in children. Pediatrics. 2016;138(1):1–14. DOI: https://doi.org/10.1542/peds.2015-4126
Karagüzel G, Sakarya NP, Bahadır S, Yaman S, Ökten A. Vitamin D status and the effects of oral vitamin D treatment in children with vitiligo: A prospective study. Clin Nutr ESPEN. 2016;15:1–4. DOI: https://doi.org/10.1016/j.clnesp.2016.05.006
Polat M, Özge U. Topical vitamin D analogs. Dalam : Relhan V, Garg VK, Ghunawat S, Mahajan K, penyunting. Comprehensive Textbook on Vitiligo. Edisi ke-1. Roca Baton: CRC Press; 2021.h.119–23. DOI: https://doi.org/10.1201/9781315112183-23
Gianfaldoni S, Tchernev G, Wollina U, Lotti J, Satolli F, França K, dkk. Vitiligo in children: A better understanding of the disease. Open Access Maced J Med Sci. 2018;6(1):181–4. DOI: https://doi.org/10.3889/oamjms.2018.040
Jakku R, Thappatla V, Kola T, Kadarla RK. Vitiligo-an overview. Asian J Pharm Res Dev. 2019;7(5):113–23.
Wan J, Lin F, Zhang W, Xu A, Degiorgis J, Lu H, dkk. Novel approaches to vitiligo treatment via modulation of mTOR and NF-κb pathways in human skin melanocytes. Int J Biol Sci. 2017;13(3):391. DOI: https://doi.org/10.7150/ijbs.17318
Li S, Zhu G, Yang Y, Jian Z, Guo S, Dai W, dkk. Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes. J Allergy Clin Immunol. 2017;140(1):177–89. DOI: https://doi.org/10.1016/j.jaci.2016.10.013
Bolognia JL, Orlow SJ. Melanocyte-biology. Dalam : Bolognia JL, Schaffer JV, Cerroni L, penyunting. Dermatology. Edisi ke-4. China: Elsevieer;2018.h.1075-85.
Didona D, Didona B, Paolino G, Dante R, Caro C. Etiopathogenesis. Dalam : Relhan V, Garg VK, Ghunawat S, Mahajan K, penyunting. Comprehensive Textbook on Vitiligo. Edisi ke-1. Roca Baton: CRC Press;2021.h.21–8. DOI: https://doi.org/10.1201/9781315112183-5
Arora A, Kumaran M. Pathogenesis of vitiligo: An update. Pigment Int. 2017;4(2):65. DOI: https://doi.org/10.4103/2349-5847.219673
Majumder PP. Genetics and Prevalence of Vitiligo Vulgaris. Dalam: Hann SK, Nordlund JJ, and Lerner AB, penyunting. Vitiligo: A monograph on the basic and clinical science. Oxford : Blackwell Science Ltd;2000,h.18–20.
Frisoli ML, Harris JE. Vitiligo: Mechanistic insights lead to novel treatments. J Allergy Clin Immunol. 2017;140(3):654–62. DOI: https://doi.org/10.1016/j.jaci.2017.07.011
Xie H, Zhou F, Liu L, Zhu G, Li Q, Li C, dkk. Vitiligo: How do oxidative stress-induced autoantigens trigger autoimmunity? J Dermatol Sci. 2016;81:3-9. DOI: https://doi.org/10.1016/j.jdermsci.2015.09.003
Yi X, Guo W, Shi Q, Yang Y, Zhang W, Chen X, dkk. SIRT3-dependent mitochondrial dynamics remodeling contributes to oxidative stress-induced melanocyte degeneration in vitiligo. Theranostics. 2019;9:1614-33. DOI: https://doi.org/10.7150/thno.30398
Dwivedi M, Laddha NC, Shah K, Shah BJ, Begum R. Involvement of interferon-gamma genetic variants and intercellular adhesion molecule-1 in onset and progression of generalized vitiligo. J Interferon Cytokine Res. 2013;33:646-59. DOI: https://doi.org/10.1089/jir.2012.0171
Miniati A, Weng Z, Zhang B, Therianou A, Vasiadi M, Nicolaidou E, dkk. Stimulated human melanocytes express and release interleukin-8, which is inhibited by luteolin: relevance to early vitiligo. Clin Exp Dermatol. 2014;39:54-7. DOI: https://doi.org/10.1111/ced.12164
Iannella G, Greco A, Didona D, Didona B, Granata G, Manno A, dkk. Vitiligo: pathogenesis, clinical variants and treatment approaches. Autoimmun Rev. 2016;15:335-43. DOI: https://doi.org/10.1016/j.autrev.2015.12.006
Klarquist J, Eby JM, Henning SW, Li M, Wainwright DA, Westerhof W, dkk. Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin. Pigment Cell Melanoma Res. 2016;29:379-84. DOI: https://doi.org/10.1111/pcmr.12458
Njoo MD, Westerhof W. Vitiligo. Pathogenesis and treatment. Am J Clin Dermatol. 2001;2(3):167–81. DOI: https://doi.org/10.2165/00128071-200102030-00006
Mohammed GF, Gomaa AH, Al-Dhubaibi MS. Highlights in pathogenesis of vitiligo. World Journal of Clinical Cases: WJCC. 2015; 3(3): 221.Mazereeuw-Hautier J, Harper J. Vitiligo. Dalam: Harper J, Oranje A, Prose N, penyunting. Textbook of pediatric d DOI: https://doi.org/10.12998/wjcc.v3.i3.221
ermatology. Edisi ke-2. Oxford: Blackwell Publishing Ltd;2006.h.1041-56.
Handa S, Dogra S. Epidemiology of childhood vitiligo: A study of 625 patients from north India. Pediatr Dermatol. 2003;20:207-10. DOI: https://doi.org/10.1046/j.1525-1470.2003.20304.x
Prcic S, Djuran V, Mikov A, Mikov I. Vitiligo in children. Pediatr Dermatol 2007;24: 666. DOI: https://doi.org/10.1111/j.1525-1470.2007.00565.x
Messenger AG, Sinclair RD, Farrant P, de Berker DAR. Acquired disorders of hair. Dalam : Burns T, Breathnach S, Cox N, Griffiths C, penyunting. Rook’s textbook of dermatology. Edisi ke-8. Oxford: Wiley-Blackwell;2010.h.66.1-66.100. DOI: https://doi.org/10.1002/9781444317633.ch66
Hercogova J, Schwartz RA, Lotti TM. Classification of vitiligo: A challenging endeavor. Dermatol Ther. 2012;25:10-6. DOI: https://doi.org/10.1111/dth.12010
Lotti T, Hercogová J, penyunting. Vitiligo – problems and solutions. New York, NY: Marcel Dekker Inc.;2004:18–66.
Onunu AN, Kubeyinje EP. Vitiligo in the Nigerian African: A study on 351 patients in Benin City in Nigeria. Int J Dermatol. 2003:42:800–2. DOI: https://doi.org/10.1046/j.1365-4362.2003.01908.x
Lotti T, D'Erme AM. Vitiligo as a systemic disease. Clinics in dermatology. 2014;32(3):430-4. DOI: https://doi.org/10.1016/j.clindermatol.2013.11.011
Iacovelli P, Sinagra JL, Vidolin AP, Marenda S, Capitanio B, Leone G, dkk. Relevance of thyroiditis and of other autoimmune diseases in children with vitiligo. Dermatology. 2005;210(1):26-30. DOI: https://doi.org/10.1159/000081479
Palit A, Inamadar AC. Childhood vitiligo. IJDVL. 2012;78(1):30. DOI: https://doi.org/10.4103/0378-6323.90944
Marçon CR, Maia M. Albinism: Epidemiology, genetics, cutaneous characterization, psychosocial factors. An Bras Dermatol. 2019;94(5):503–20. DOI: https://doi.org/10.1016/j.abd.2019.09.023
Federico JR, Krishnamurthy K. Albinism. Treasure Islands: StatPearls Publishing;2021.h.1–10.
Goh BK, Pandya AG. Presentations, signs of activity and differential diagnosis of vitiligo. Dermatol Clin. 2017;35(2):135–44. DOI: https://doi.org/10.1016/j.det.2016.11.004
Patel TJ, Rodney IJ, Halder RM. Disorders of hypopigmentation and depigmentation. Dalam : Vashi NA, Maibach HI, penyunting. Dermatoanthropology of ethnic skin and hair. Edisi ke-1. Cham: Springer International Publishing;2017.h.215–31. DOI: https://doi.org/10.1007/978-3-319-53961-4_14
Saleem MD. Biology of human melanocyte development, piebaldism, and waardenburg syndrome. Pediatr Dermatol. 2019;36(1):72–84. DOI: https://doi.org/10.1111/pde.13713
Cabral-Pacheco GA, Garza-Veloz I, Campuzano-García AE, Díaz-Alonso AP, Flores-Morales V, Rodriguez-Sanchecabraz IP, dkk. Expression levels of inflammatory and oxidative stress-related genes in skin biopsies and their association with pityriasis alba. Medicina (B Aires). 2020;56(7):1–11. DOI: https://doi.org/10.3390/medicina56070359
Sharquie KE, Salman HA, Yaseen AK. Psoriasis and vitiligo are close relatives. Clin Cosmet Investig Dermatol. 2017;10:341–5. DOI: https://doi.org/10.2147/CCID.S142819
Rendon A, Schäkel K. Psoriasis pathogenesis and treatment. Int J Mol Sci. 2019;20(1475):1–28. DOI: https://doi.org/10.3390/ijms20061475
Sharquie KE, Noaimi AA, Abdulkadhim LM. Pityriasis alba versus vitiligo clinical and histopathological study. J Cosmet Dermatological Sci Appl. 2018;8(3):140–50. DOI: https://doi.org/10.4236/jcdsa.2018.83016
Maymone MBC, Watchmaker JD, Dubiel M, Wirya SA, Shen LY, Vashi NA. Common skin disorders in pediatric skin of color. J Pediatr Heal Care. 2019;33(6):727–37. DOI: https://doi.org/10.1016/j.pedhc.2019.04.019
Wang Y-J, Chang C-C, Cheng K-L. Wood’s lamp for vitiligo disease stability and early recognition of initiative pigmentation after epidermal grafting. Int Wound J. 2017;14(6):1391–4. DOI: https://doi.org/10.1111/iwj.12800
El-Husseiny R, Abd-Elhaleem A, Salah El-Din W, Abdallah M. Childhood vitiligo in Egypt: clinico-epidemiologic profile of 483 patients. J Cosmet Dermatol. 2021;20(1):1–6. DOI: https://doi.org/10.1111/jocd.13451
Thng S, Chuah SY, Gan EY. Age and vitiligo: childhood, pregnancy, and late-onset vitiligo. Dalam : Picardo M, Taïeb A, penyunting. Vitiligo. Edisi ke-1. Cham: Springer Natu; 2019.h.141–51. DOI: https://doi.org/10.1007/978-3-319-62960-5_14
Taïeb A, and Picardo M; VETF Members. The definition and assessment of vitiligo: A consensus report of the Vitiligo European Task Force. Pigment Cell Res. 2007;20:27–35. DOI: https://doi.org/10.1111/j.1600-0749.2006.00355.x
Al Aboud DM, Gossman W. Woods light. Treasure Islands: StatPearls Publishing; 2020.h.1–5.
Taïeb A, Seneschal J, Mazereeuw-Hautier J. Special Considerations in Children with Vitiligo. Dermatologic clinics. 2017;35(2):229-33. DOI: https://doi.org/10.1016/j.det.2016.11.011
Taieb AV, Alomar A, Böhm M, Dell’Anna ML, De Pase A, Eleftheriadou V, dkk. Guidelines for the management of vitiligo: the European Dermatology Forum consensus. British Journal of Dermatology. 2013;168(1):5-19. DOI: https://doi.org/10.1111/j.1365-2133.2012.11197.x
Neema S, Khunger N. Vitiligo and other disorder of hypopigmentation. Dalam: Chatterjee M, Neema S, Malakar S. Dermoscopy in darker skin. India : Jaypee brother medical publisher;2018.h.35-8. DOI: https://doi.org/10.5005/jp/books/13079_8
Camisa C, Garofola C. Topical Immunomodulatory Drugs: Topical Corticosteroids. Dalam: Wolverton SE, penyunting. Comprehensive Dermatologic Drug Therapy. Edisi ke-4. Philadelpia: Elsevier;2021.h.511-27. DOI: https://doi.org/10.1016/B978-0-323-61211-1.00045-0
Van der Veen JPW, Wind BS, Taieb. A Topical corticosteroids. Dalam: Picardo M, Taieb A, penyunting. Vitiligo. New York : Springer;2010.h.327-38. DOI: https://doi.org/10.1007/978-3-540-69361-1_38
Silverberg NB. Pediatric vitiligo. Pediatric Clinics. 2014;61(2):347-66. DOI: https://doi.org/10.1016/j.pcl.2013.11.008
Udompataikul M, Boonsupthip P, Siriwattanagate R. Effectiveness of 0.1% topical takrolimus in adult and children patients with vitiligo. J. Dermatol. 2011;38(6):536–40. DOI: https://doi.org/10.1111/j.1346-8138.2010.01067.x
Silverberg JI, Silverberg NB. Topical takrolimus is more effective for treatment of vitiligo in patients of skin of color. J. Drugs Dermatol. 2011;10(5):507–10.
Silverberg NB, Lin P, Travis L, Farley‐Li J, Mancini AJ, Wagner AM, dkk. Takrolimus ointment promotes repigmentation of vitiligo in children: A review of 57 cases. J. Am. Acad. Dermatol. 2004;51(5):760–6. DOI: https://doi.org/10.1016/j.jaad.2004.05.036
Seirafi H, Farnaghi F, Firooz A, Vasheghani-Farahani A, Alirezaie NS, Dowlati Y. Pimecrolimus cream in repigmentation of vitiligo. Dermatology. 2007;214(3):253-9. DOI: https://doi.org/10.1159/000099592
Mayoral FA, Gonzalez C, Shah NS, Arciniegas C. Repigmentation of vitiligo with pimecrolimus cream: A case report. Dermatology. 2003;207(3):322-3. DOI: https://doi.org/10.1159/000073099
Agarwal K, Podder I, Kassir M, Vojvodic A, Schwartz RA, Wollina U, dkk. Therapeutic options in vitiligo with special emphasis on immunomodulators: A comprehensive update with review of literature. Dermatologic therapy. 2020;33(2):13215. DOI: https://doi.org/10.1111/dth.13215
Faria AR, Tarlé RG, Dellatorre G, Mira MT, Castro CC. Vitiligo-Part 2-classification, histopathology and treatment. Anais brasileiros de dermatologia. 2014;89(5):784-90. DOI: https://doi.org/10.1590/abd1806-4841.20142717
Staricco RG. Activation of amelanotic melanocytes in the outer root sheath of the hair follicle following ultraviolet exposure. J Invest Dermatol. 1962;39:163–4. DOI: https://doi.org/10.1038/jid.1962.97
Parsad D, Kanwar AJ, Kumar B. Psoralen-ultraviolet A vs. narrow-band ultraviolet B phototherapy for the treatment of vitiligo. J Eur Acad Dermatol Venereol. 2006;20:175–7. DOI: https://doi.org/10.1111/j.1468-3083.2006.01413.x
Gianfaldoni S, Wollina U, Tchernev G, Lotti J, França K, Lotti T. Vitiligo in children: A review of conventional treatments. OAMJMS. 2018;6(1):213. DOI: https://doi.org/10.3889/oamjms.2018.054
Novaković LB. UVA‐based phototherapy: PUVA, PUVA‐Sol, and UVA1 phototherapy. Dalam: Gupta S, Olsson MJ, Parsad D, Lim HW, van Geel N, Pandya AG, penyunting. Vitiligo: Medical and surgical management. edisi ke-1. Hoboken: Wiley Blackwell;2018.h.105–12. DOI: https://doi.org/10.1002/9781118937303.ch13
Bae JM, Jung HM, Hong BY, Lee JH, Choi WJ, Lee JH, dkk . Phototherapy for vitiligo: A systematic review and meta-analysis. JAMA Dermatology. 2017;153(7):1–9. DOI: https://doi.org/10.1001/jamadermatol.2017.0002
Hamzavi I, Jain H, McLean D, Shapiro J. Parametric modelling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool, the vitiligo area scoring index. Arch Dermatol. 2004;140:677–83. DOI: https://doi.org/10.1001/archderm.140.6.677
Kanwar AJ, Dogra S. Narrow‐band UVB for the treatment of generalized vitiligo in children. Clin Exp Dermatol. 2005;30(4):332–6. DOI: https://doi.org/10.1111/j.1365-2230.2005.01837.x
Cho S, Zheng Z, Park YK, Roh MR. The 308‐nm excimer laser: A promising device for the treatment of childhood vitiligo. Photodermatology, photoimmunology & photomedicine. 2011;27(1):24-9. DOI: https://doi.org/10.1111/j.1600-0781.2010.00558.x
Park KK, Liao W, Murase JE. A review of monochromatic excimer light in vitiligo. Br J Dermatol. 2012;167(3):468–78. DOI: https://doi.org/10.1111/j.1365-2133.2012.11008.x
Nisticò S, Chiricozzi A, Saraceno R, Schipani C, Chimenti S. Vitiligo treatment with monochromatic excimer light and takrolimus: Results of an open randomized controlled study. Photomed Laser Surg. 2012;30(1):26–30. DOI: https://doi.org/10.1089/pho.2011.3029
Majid I, Masood Q, Hassan I, Khan D, and Chisti M. Childhood vitiligo: Response to methylprednisolone oral minipulse therapy and topical fluticasone combination. Indian J Dermatol. 2009;54:124–7. DOI: https://doi.org/10.4103/0019-5154.53185
Sarkar R, Bansal S. Childhood vitiligo. Dalam : Oranje AP, Al-Mutairi N, Shwayder T, penyunting. Practical Pediatric Dermatology: Controversies in diagnosis and treatment. Edisi ke-1. Cham;2016.h.133–9.
Taneja A, Kumari A, Vyas K, Khare A, Gupta L, Mittal A. Cyclosporine in treatment of progressive vitiligo: An open-label, single-arm interventional study. IJDVL. 2019; 85(5):528–31. DOI: https://doi.org/10.4103/ijdvl.IJDVL_656_18
Choi Y, Lim WS, Jin SY, Lee JH, Lee SH, Lee AY. Vitiligo lesions improved after oral cyclosporine in a patient with vitiligo and atopic dermatitis. Korean J Dermatol. 2012;50(2):159-62.
Nageswaramma S, Vani T, Indira N. Efficacy of methotrexate in Vitiligo. IOSR Journal of Dental and Medical Sciences. 2018;17(5):16–9.
Dugoua JJ, Mills E, Perri D, Koren G. Safety and efficacy of ginkgo (Ginkgo biloba) during pregnancy and lactation. Can J Clin Pharmacol. 2006;13(3):277–84.
Szczurko O, Shear N, Taddio A, Boon H. Ginkgo biloba for the treatment of vitilgo vulgaris: An open label pilot clinical trial. BMC Complement Altern Med. 2011;11:21. DOI: https://doi.org/10.1186/1472-6882-11-21
Ramien ML, Ondrejchak S, Gendron R, Hatami A, McCuaig CC, Powell J, dkk. Quality of life in pediatric patients before and after cosmetic camouflage of visible skin conditions. J Am Acad Dermatol. 2014;71(5):935–40. DOI: https://doi.org/10.1016/j.jaad.2014.07.029
Sarveswari KN. Cosmetic camuflage in vitiligo. Indian J Dermatol. 2010;55(3):211-4. DOI: https://doi.org/10.4103/0019-5154.70663
Budania A, Parsad D, Kanwar AJ, Dogra S. Comparison between autologous noncultured epidermal cell suspension and suction blister epidermal grafting in stable vitiligo: A randomized study. Br J Dermatol. 2012;167(6):1295-301. DOI: https://doi.org/10.1111/bjd.12007
Holla AP, Kumar R, Parsad D, Kanwar AJ. Modified procedure of noncultured epidermal suspension transplantation: Changes are the core of vitiligo surgery. J Cutan Aesthet Surg 2011;4:44–5. DOI: https://doi.org/10.4103/0974-2077.79192
Gupta S, Shroff S, Gupta S. Modified technique of suction blistering for epidermal grating in vitiligo. Int J Dermatol. 1999;38:306–9. DOI: https://doi.org/10.1046/j.1365-4362.1999.00702.x
Gauthier Y, Surleve-Bazeille J. Autologous grafting with noncultured melanocytes: a simplified method for treatment of depigmented lesions. J Am Acad Dermatol. 1992;26:191–4. DOI: https://doi.org/10.1016/0190-9622(92)70024-A
Falabella R. Epidermal grafting: An original technique and its application in achromic and 76. granulating areas. Arch Dermatol. 1971;104:592–600. DOI: https://doi.org/10.1001/archderm.104.6.592
Tsuchiyama K, Watabe A, Sadayasu A, Onodera N, Kimura Y, Aiba S. Successful treatment of segmental vitiligo in children with the combination of 1-mm minigrafts and phototherapy. Dermatology. 2016;232:237–41. DOI: https://doi.org/10.1159/000442666
Wang HL, Avila G. Platelet rich plasma: myth or reality? Eur J Dent. 2007;1:192–4. DOI: https://doi.org/10.1055/s-0039-1698338
Hesseler MJ, Shyam N. Platelet-rich plasma and its utility in medical dermatology: A systematic review. J Am Acad Dermatol. 2019;81:834–46. DOI: https://doi.org/10.1016/j.jaad.2019.04.037
Woodell-May J, Matuska A, Oyster M, Welch Z, O'Shaughnessey K, Hoeppner J. Autologous protein solution inhibits MMP-13 production by IL-1beta and TNF alpha-stimulated human articular chondrocytes. J Orthop Res. 2011;16:1320–6. DOI: https://doi.org/10.1002/jor.21384
Ibrahim ZA, El-Ashmawy AA, El-Tatawy RA, Sallam FA. The effect of platelet-rich plasma on the outcome of short-term narrowband-ultraviolet B phototherapy in the treatment of vitiligo: A pilot study. J Cosmet Dermatol. 2016;15:108–16. DOI: https://doi.org/10.1111/jocd.12194
Abdelghani R, Ahmed NA, Darwish HM. Combined treatment with fractional carbon dioxide laser, autologous platelet-rich plasma, and narrow band ultraviolet B for vitiligo in different body sites: A prospective, randomized comparative trial. J Cosmet Dermatol. 2017;17:365–72. DOI: https://doi.org/10.1111/jocd.12397
Kadry M, Tawfik A, Abdallah N, Badawi A, Shokeir H. Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: A comparative study. Clin Cosmet Investig Dermatol. 2018;11:551–5. DOI: https://doi.org/10.2147/CCID.S178817
Khattab FM, Abdelbary E, Fawzi M. Evaluation of combined excimer laser and platelet‐rich plasma for the treatment of nonsegmental vitiligo: A prospective comparative study. Journal of cosmetic dermatology. 2020;19(4):869-77. DOI: https://doi.org/10.1111/jocd.13103
Mercuri SR, Vollono L, Paolino G. The usefulness of platelet-rich plasma (PRP) for the treatment of vitiligo: State of the art and review. Drug Des Devel Ther. 2020;14:1749. DOI: https://doi.org/10.2147/DDDT.S239912
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