Terapi Probiotik Pada Akne Vulgaris
DOI:
https://doi.org/10.56951/medicinus.v34i2.76Kata Kunci:
akne vulgaris, probiotikAbstrak
Akne vulgaris (AV) adalah penyakit inflamasi kronik kulit yang mengenai unit pilosebasea dan mengakibatkan kelainan noninflamasi berupa komedo terbuka (blackhead) dan komedo tertutup (whitehead) serta adanya tanda inflamasi seperti papul, pustul dan nodul. Banyak faktor yang berkontribusi terhadap patogenesis AV termasuk mikrobioma kulit seperti Propionibacterium acnes (P. acnes) dan Malassezia spp. yang dikaitkan dengan perkembangan AV melalui pengaruhnya terhadap sekresi sebum, pembentukan komedo dan respons inflamasi. Terapi antibiotik dengan target P. acnes telah lama menjadi terapi utama AV dimana terapi tersebut ternyata dapat mempengaruhi komposisi dari mikrobioma kulit. Seiring dengan meningkatnya resistensi antibiotik, pengetahuan tentang mikrobioma kulit yang terkait dengan AV menjadi sangat relevan dan penting untuk menjadi dasar alternatif pilihan terapi AV.
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Das S, Reynolds R. Recent Advances In Acne Pathogenesis: Implications For Therapy. Amrican Journal Clinic Dermatology. 2014;15(6):479-88. DOI: https://doi.org/10.1007/s40257-014-0099-z
Seaton E. Pathogenesis And Recommended Management Of Acne. Prescriber. 2011;22(21):46-57. DOI: https://doi.org/10.1002/psb.832
Xu H, Li H. Acne, the Skin Microbiome, and Antibiotic Treatment. American Journal of Clinical Dermatology. 2019:1-10.
Bowe W, Logan A. Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future? Gut Pathog. 2011:1-11. DOI: https://doi.org/10.1186/1757-4749-3-1
Dietert R, Dietert J. Review: the microbiome and sustainable healthcare. Healthcare. 2015;3:100-29. DOI: https://doi.org/10.3390/healthcare3010100
Lederberg J, McCray A. Ome Sweet Omics—a genealogical treasury of words. Scientist. 2001;15:8.
Boon E, Meehan C, Whidden C, Wong D, Langille M, Beiko R. Interactions in the microbiome: communities of organisms and communities of genes. FEMS Microbiol Rev. 2013;38:1-59. DOI: https://doi.org/10.1111/1574-6976.12035
Ursell L, Metcalf J, Parfrey L, Knight R. Defining the human microbiome. Nutr Rev. 2012;70:S38-44. DOI: https://doi.org/10.1111/j.1753-4887.2012.00493.x
Houtman J, highlander S. The human microbiome: your own personal ecosystem. Annu Rev Genomics Hum Genet. 2012;13:151-79. DOI: https://doi.org/10.1146/annurev-genom-090711-163814
Hair M, Sharpe J. Fast facts about the human microbiome Washington: University of Washington: Center for ecogenetics & Environmental Health; Tersedia dari: http://depts.washington.edu/ceeh/downloads/FF_Microbiome.pdf. Diakses tanggal 07 Maret 2020.
Grice E, Segre J. The skin microbiome. Nat Rev Microbiol. 2011;9:244-53. DOI: https://doi.org/10.1038/nrmicro2537
Findley K, Oh J, Yang J, Conlan S, Deming C, Meyer J, et al. Topographic diversity of fungal and bacterial communities in human skin. Nature. 2013;498:367-70. DOI: https://doi.org/10.1038/nature12171
Byrd A, Belkaid Y, Segre J. The human skin microbiome. Nat Rev Microbiol. 2018:1-13. DOI: https://doi.org/10.1038/nrmicro.2017.157
Feng H, Shuda M, Chang Y, Moore P. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science. 2008;319:1096-100. DOI: https://doi.org/10.1126/science.1152586
Hannigan G, Meisel J, Tyldsley A, Zheng Q, Hodkinson B, SanMiguel A, et al. The human skin doublestranded dna virome: topographical and temporal diversity, genetic enrichment, and dynamic associations with the host microbiome. mBio. 2015;6:e01578-15. DOI: https://doi.org/10.1128/mBio.01578-15
Nakatsuji T, Chiang H, Jiang S, Nagarajan H, Zengler K, Gallo R. The microbiome extends to subepidermal compartments of normal skin. Nat Commun. 2013;4:1431-9. DOI: https://doi.org/10.1038/ncomms2441
Zeeuwen P, Boekhorst J, Bogaard Evd, Koning Hd, Kerkhof Pvd, Saulnier D, et al. Microbiome dynamics of human epidermis following skin barrier disruption. Genome Biol. 2012;13:R101. DOI: https://doi.org/10.1186/gb-2012-13-11-r101
FAO/WHO. Guidelines for the Evaluation of Probiotics in Food. 2002. Tersedia dari: https://www.who.int/foodsafety/fs_management/en/probiotic_guidelines.pdf. Diakses tanggal 05 Maret 2020.
Lee Y. Effects of Diet on Gut Microbiota Profile and the Implications for Health and Disease. Biosci Microbiota Food Health. 2013;32(1):1-12. DOI: https://doi.org/10.12938/bmfh.32.1
Sanchez B, Delgado S, Blanco-Miguez A, Lourenco A, Gueimonde M, Margolles A. Probiotics, gut microbiota, and their influence on host health and disease. Mol Nutr Food Res. 2017;61:1. DOI: https://doi.org/10.1002/mnfr.201600240
Slavin J. Fiber and prebiotics: mechanisms and health benefits. Nutrients. 2013;5(4):1417-35. DOI: https://doi.org/10.3390/nu5041417
Findley K, Grice E. The skin microbiome: a focus on pathogens and their association with skin disease. PLoS Pathog. 2014;10(10):e1004436. DOI: https://doi.org/10.1371/journal.ppat.1004436
Fitz-Gibbon S, Tomida S, Chiu B, Nguyen1 L, Du C, Liu M, et al. Propionibacterium acnes strain populations in the human skin microbiome associated with acne. J Invest Dermatol. 2013;133:2152-60. DOI: https://doi.org/10.1038/jid.2013.21
Porubsky C, Glass A, Comeau V, Buckley C, Goodman M, Kober M. The Role of Probiotics in Acne and Rosacea. IntechOpen. 2018:1-16. DOI: https://doi.org/10.5772/intechopen.79044
Zhang H, Liao W, Chao W, Chen Q, Zeng H, Wu C, et al. Risk factors for sebaceous gland diseases and their relationship to gastrointestinal dysfunction in Han adolescents. J Dermatol. 2008;3(9):555-61. DOI: https://doi.org/10.1111/j.1346-8138.2008.00523.x
Stokes J, Pillsbury D. The effect on the skin of emotional and nervous states: III. Theoretical and practical consideration of a gastro-intestinal mechanism. Arch Derm Syphilol. 1930;22:962-93. DOI: https://doi.org/10.1001/archderm.1930.01440180008002
Ghoshal U, Ghoshal U. Small intestinal bacterial overgrowth and other intestinal disorders. Gastroenterol Clin North Am. 2017;46(1):103-20. DOI: https://doi.org/10.1016/j.gtc.2016.09.008
Strickler A, Kolmer J, Schamberg J. Complement fixation in acne vulgaris. J Cutaneous Dis. 1916;34:166-78.
Siver R. Lactobacillus for the control of acne. J Med Soc New Jersey. 1961;59:52-3.
Marchetti F, Capizzi R, Tulli A. Efficacy of regulators of the intestinal bacterial flora in the therapy of acne vulgaris. Clin Ter. 1987(122):339-43.
Kim J, Ko Y, Park Y, Kim N, Ha W, Cho Y. Dietary effect of lactoferrinenriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition. 2010(26):902-9. DOI: https://doi.org/10.1016/j.nut.2010.05.011
Cazzola M, Tompkins T, Matera M. Immunomodulatory impact of a synbiotic in T(h)1 and T(h)2 models of infection. Ther Adv Respir Dis. 2010(4):259-70. DOI: https://doi.org/10.1177/1753465810379009
Peyri J. Topical bacteriotherapy of the skin. J Cutaneous Dis. 1912;30:688-9.
Breiden B, Sandhoff K. The role of sphingolipid metabolism in cutaneous permeability barrier formation. Biochim Biophys Acta. 2014;1841(3):441-52. DOI: https://doi.org/10.1016/j.bbalip.2013.08.010
Pavicic T, Wollenweber U, Farwick M, Korting H. Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris. Int J Cosmet Sci. 2007;29:181-90. DOI: https://doi.org/10.1111/j.1467-2494.2007.00378.x
Lee W, Jung H, Lee H, Kim B, Lee S, Kim dW. Influence of substance-P on cultured sebocytes. Arch Dermatol Res. 2008(300):311-6. DOI: https://doi.org/10.1007/s00403-008-0854-1
Kang B, Lee JSG, Kim J, Kim S, Han Y, Kang H, et al. Antimicrobial activity of enterocins from Enterococcus faecalis SL-5 against Propionibacterium acnes, the causative agent in acne vulgaris, and its therapeutic effect. J Microbiol. 2009(47):101-9. DOI: https://doi.org/10.1007/s12275-008-0179-y
Brook I. Bacterial interference. Crit Rev Microbiol. 1999(25):155-72. DOI: https://doi.org/10.1080/10408419991299211
Zhang Z, Mu L, Tang J, Duan Z, Wang F, Wei L, et al. A small peptide with therapeutic potential for inflammatory acne vulgaris. pLoS One. 2013;8(8):e72923. DOI: https://doi.org/10.1371/journal.pone.0072923
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